The type of lubricant used when trying to get pregnant can affect the chances of conception. PRE SEED is a sperm friendly vaginal lubricant recommended for women who are trying to conceive but experience The most pregnancy friendly lubricants are the water based kinds. These lubes are water soluble, which means they dissolve in water. They're safer for you and your baby, typically because they contain fewer chemicals than What to look for in a lubricant while you're pregnant BabyCenter Pregnancy Safe Lubricants Best Options for Pregnancy Can your lube affect your chances of getting pregnant? Yes some lubricants can make it harder for sperm to reach the egg. Look for sperm safe or fertility friendly formulas that mimic your